Clinical Guidelines

Who Needs a Liver Transplant?

A transplant is considered when the liver is irreversibly damaged and can no longer support the body's vital functions.

Chronic Condition

End-Stage Liver Disease (Cirrhosis)

Advanced scarring (cirrhosis) occurs over years of injury. When the damage becomes permanent, medicines can no longer reverse the condition. At this stage, a transplant is the only cure.

  • Jaundice (Yellowing)
  • Ascites (Fluid Buildup)
  • Confusion/Memory Loss
  • Chronic Weakness
Medical Emergency

Acute Liver Failure

This happens suddenly, often over hours or days. It is a critical emergency. If the liver stops working due to toxins, drugs, or infections and recovery is not possible, a transplant is needed urgently.

  • Sudden Confusion
  • Rapid Jaundice
  • Severe Vomiting
  • Risk of Coma
Oncology

Liver Cancer (HCC)

Hepatocellular carcinoma is the most common primary liver cancer. A transplant is often considered in early-stage cases where a small tumor exists alongside an otherwise failing or diseased liver.

  • Abdominal Pain
  • Unexplained Weight Loss
  • Loss of Appetite
  • Swelling of Abdomen
Inherited Disorders

Rare Metabolic Diseases

Present from birth, these inherited disorders prevent the liver from processing certain substances. Even with medication and diet, toxins may build up, slowly damaging the entire body.

  • Poor Growth
  • Extreme Fatigue
  • Seizures
  • Dangerous Toxin Build-up

Consult a Specialist

Transplantation is a complex decision based on individual medical scores and urgency. Early consultation is the first step toward recovery.

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